Conservative surgery in the treatment of giant cell tumor of the sacrum: 35 years' experience.
Publication/Presentation Date
2-1-2016
Abstract
OBJECT There is no consensus regarding the appropriate treatment of sacral giant cell tumor (GCT). There are 3 main management problems: tumor control, neurological loss, and pelvic instability. The objective of this study was to examine oncological, neurological, and structural outcomes of sacral GCT after intralesional excision and local intraoperative adjunctive treatment. METHODS The authors retrospectively reviewed the records of 24 patients with sacral GCT who underwent conservative surgery (intralesional resection/curettage) at Memorial Sloan Kettering Cancer Center from 1973 through 2012. They analyzed patient demographic data, tumor characteristics, and operative techniques, and examined possible correlations with postoperative functional outcomes, complications, recurrence, and mortality. RESULTS There were 7 local recurrences (30%) and 3 distant recurrences (13%). Three of 24 patients (12.5%) had significant neurological loss after treatment-specifically, severe bowel and/or bladder dysfunction, but all regained function within 1-4 years. Larger tumor size (> 320 cm
Volume
24
Issue
2
First Page
228
Last Page
240
ISSN
1547-5646
Published In/Presented At
Domovitov, S. V., Chandhanayingyong, C., Boland, P. J., McKeown, D. G., & Healey, J. H. (2016). Conservative surgery in the treatment of giant cell tumor of the sacrum: 35 years' experience. Journal of neurosurgery. Spine, 24(2), 228–240. https://doi.org/10.3171/2015.4.SPINE13215
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
26516662
Department(s)
Administration and Leadership
Document Type
Article