Transplantation-mediated alloimmune thrombocytopenia: Guidelines for utilization of thrombocytopenic donors.

Authors

• Geraldine C Diaz
• Joan Prowda
• Irene J Lo
• Gowthami M Arepally
• Neal Evans
• Yvonne Wheeless
• Benjamin Samstein
• James V Guarrera
• John F Renz

Publication/Presentation Date

12-1-2008

Abstract

Transplantation-mediated alloimmune thrombocytopenia (TMAT) is donor-derived thrombocytopenia following solid-organ transplantation. To date, no clear consensus on the appropriateness of organ utilization from cadaver donors with a history of idiopathic thrombocytopenia purpura (ITP) has emerged. Herein is reported a devastating case of TMAT following liver transplantation utilizing an allograft from a donor with ITP that resulted in allograft failure. The literature is reviewed in this context to propose preliminary guidelines regarding utilization of allografts from cadaver donors with a history of ITP.

Volume

14

Issue

12

First Page

1803

Last Page

1809

ISSN

1527-6473

Published In/Presented At

Diaz, G. C., Prowda, J., Lo, I. J., Arepally, G. M., Evans, N., Wheeless, Y., Samstein, B., Guarrera, J. V., & Renz, J. F. (2008). Transplantation-mediated alloimmune thrombocytopenia: Guidelines for utilization of thrombocytopenic donors. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 14(12), 1803–1809. https://doi.org/10.1002/lt.21539

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

19025920

Department(s)

Administration and Leadership

Document Type

Article