Implementing an innovated preservation technology: The American Society of Transplant Surgeons' (ASTS) Standards Committee White Paper on Ex Situ Liver Machine Perfusion.
Publication/Presentation Date
8-1-2018
Abstract
The pervasive shortage of deceased donor liver allografts contributes to significant waitlist mortality despite efforts to increase organ donation. Ex vivo liver perfusion appears to enhance preservation of donor organs, extending viability and potentially evaluating function in organs previously considered too high risk for transplant. These devices pose novel challenges for organ allocation, safety, training, and finances. This white paper describes the American Society of Transplant Surgeons' belief that organ preservation technology is a vital advance, but its use should not change fundamental aspects of organ allocation. Additional data elements need to be collected, made available for organ assessment by transplant professionals to allow determination of organ suitability in the case of reallocation and incorporated into risk adjustment methodology. Finally, further work is needed to determine the optimal strategy for management and oversight of perfused organs prior to transplantation.
Volume
18
Issue
8
First Page
1865
Last Page
1874
ISSN
1600-6143
Published In/Presented At
Quintini, C., Martins, P. N., Shah, S., Killackey, M., Reed, A., Guarrera, J., Axelrod, D. A., & American Society of Transplant Surgeons Standards Committee (2018). Implementing an innovated preservation technology: The American Society of Transplant Surgeons' (ASTS) Standards Committee White Paper on Ex Situ Liver Machine Perfusion. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 18(8), 1865–1874. https://doi.org/10.1111/ajt.14945
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
29791060
Department(s)
Administration and Leadership
Document Type
Article