Maximizing the Donor Potential for Patients with Acute-on-Chronic Liver Failure Listed for Liver Transplant.
Publication/Presentation Date
8-1-2023
Abstract
Owing to inherent limitations of static cold storage, marginal liver grafts from donors after circulatory death and extended criteria donors after brain death are prone to be discarded secondary to the increased risk of severe early allograft dysfunction and ischemic cholangiopathy. Marginal liver grafts resuscitated with hypothermic machine perfusion and normothermic machine perfusion demonstrate lower degree of ischemia-reperfusion injury and have decreased risk of severe early allograft dysfunction and ischemic cholangiopathy. Marginal grafts preserved by ex vivo machine perfusion technology can be used to rescue patients with acute-on-chronic liver failure who are underserved by the current deceased donor liver allocation system.
Volume
27
Issue
3
First Page
763
Last Page
775
ISSN
1557-8224
Published In/Presented At
Amin, A., Panayotova, G. G., & Guarrera, J. V. (2023). Maximizing the Donor Potential for Patients with Acute-on-Chronic Liver Failure Listed for Liver Transplant. Clinics in liver disease, 27(3), 763–775. https://doi.org/10.1016/j.cld.2023.03.016
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
37380296
Department(s)
Administration and Leadership
Document Type
Article