Availability of suitable islet donors in the United States.
Publication/Presentation Date
7-27-2007
Abstract
BACKGROUND: We characterize donor utilization for islet transplantation and estimate the number of recipients who could achieve normoglycemia through islet transplantation if the current donor pool were used.
METHODS: Potential islet donors from all United Network for Organ Sharing donors (1/00-5/04) were identified and categorized into "optimal" islet donors (16-40 yr, body mass index >27 kg/m, hemodynamically stable) or "standard" donors (as traditionally described).
RESULTS: Of 27,552 potential donors during this period, 6,140 donor pancreata were used for whole organ transplant. Of the remaining 21,412 donors, 10,417 potential islet donors were identified (9260 [88.9%] standard and 1157 [11.1%] optimal donors). Islets from only 218 donors were used for transplant, representing 8.7% of optimal donors and 2.1% of all potential islet donors.
CONCLUSION: The widespread use of isolated islets could provide insulin independence for approximately 1000 type I diabetics a year, but at current rates of islet transplant, all recipients could be transplanted with islets from ideal donors.
Volume
84
Issue
2
First Page
280
Last Page
282
ISSN
0041-1337
Published In/Presented At
Porrett, P. M., Yeh, H., Frank, A., Deng, S., Kim, J. I., Barker, C. F., & Markmann, J. F. (2007). Availability of suitable islet donors in the United States. Transplantation, 84(2), 280–282. https://doi.org/10.1097/01.tp.0000269612.84906.4a
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
17667824
Department(s)
Administration and Leadership
Document Type
Article