Like Father like Daughter: Surgical Redo Thoracoabdominal Aneurysm Repairs in a Family With Loeys-Dietz Syndrome.
Publication/Presentation Date
1-1-2025
Abstract
Loeys Dietz Syndrome (LDS) is an autosomal dominant connective tissue disorder resulting from a mutation in the transforming growth factor beta receptor (TGFBR) family of genes. It is commonly associated with the development of aortic aneurysms and dissections. We report the successful open surgical management of thoracoabdominal aneurysms in a father and daughter with Loeys-Dietz Syndrome after failed endovascular repair. The daughter required stent graft explantation, while the stent graft remained in the father. These cases highlight the importance of early genetic testing of both patients and first-degree family members in those with a strong history of aortic disease, even when there is a lack of typical connective tissue disorder associated physical exam findings and open surgical index operations.
Volume
59
Issue
1
First Page
93
Last Page
96
ISSN
1938-9116
Published In/Presented At
Chen, J. R., Shah, V. N., Pritting, C., Nooromid, M., Abai, B., & Plestis, K. (2025). Like Father like Daughter: Surgical Redo Thoracoabdominal Aneurysm Repairs in a Family With Loeys-Dietz Syndrome. Vascular and endovascular surgery, 59(1), 93–96. https://doi.org/10.1177/15385744241279139
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
39207942
Department(s)
Administration and Leadership
Document Type
Article