Sinonasal malignancy: What to do with an unexpected pathology result?
Publication/Presentation Date
1-1-2016
Abstract
BACKGROUND: Endoscopic sinus surgery has become the mainstay in surgical treatment of sinusitis and nasal polyps. While rare, diagnostic discrepancies or pathological contamination during routine specimen analysis has been described. Thus, an accurate diagnosis and indication for surgery are mandatory before proceeding with surgical intervention.
METHODS: We present the case of a 40-year-old female patient who underwent endoscopic sinus surgery (ESS) for chronic sinusitis without nasal polyposis and fragments of squamous cell carcinoma (SCC) were found in the pathology specimen.
RESULTS: We propose an algorithm to help guide physicians presented with a tissue diagnosis that does not match the clinical scenario. Moreover, we discuss strategies to help prevent medical errors and the importance of DNA genetic analysis in this situation.
CONCLUSION: When an unexpected diagnosis occurs, the pathology slides should be reviewed for a second opinion. If the unexpected diagnosis is confirmed, the tissue should undergo STR genetic analysis to ensure against tissue contamination.
Volume
37
Issue
5
First Page
473
Last Page
476
ISSN
1532-818X
Published In/Presented At
Hall, M. B., Rosen, M. R., Gill, K., & Nyquist, G. G. (2016). Sinonasal malignancy: What to do with an unexpected pathology result?. American journal of otolaryngology, 37(5), 473–476. https://doi.org/10.1016/j.amjoto.2016.04.003
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
27311347
Department(s)
Administration and Leadership
Document Type
Article