Reproducibility of fetal lung volume measurements with 3-dimensional ultrasonography.

Authors

• Juan Carlos Sabogal
• Eduardo Becker
• George Bega
• Ratana Komwilaisak
• Vincenzo Berghella
• Stuart Weiner
• Jorge Tolosa

Publication/Presentation Date

3-1-2004

Abstract

OBJECTIVE: To build a nomogram of normal fetal lung volumes and to assess the reproducibility of measurements using 3-dimensional ultrasonography.

METHODS: Inclusion criteria were healthy women, singleton normal pregnancies, reliable dating, and 20 to 30 weeks' gestation. Exclusion criteria were discordance between clinical and ultrasonographic dating, patients lost to follow-up, and birth weight disorders. Patients were scanned at intervals longer than 2 weeks. Three volumes were acquired for each patient; only data from the volume with the best image quality was used for analysis. Volumes were rated and measured by the manual tracing method. We recorded whether the clavicle was visualized. Only good-quality volumes were included in analysis. The best volume was chosen, and each lung was measured.

RESULTS: A total of 75 patients were studied over a 9-month period, from which 182 volumes were analyzed. Of the 182 volumes, 15 (8.2%) were excluded for poor quality. The remaining 167 volumes were included in the final analysis. In 83 volumes (50%), the clavicle was not visualized. The best fit for total lung volume was a second-degree polynomial regression curve. Lung volume was 10.28 mL at 20 weeks and 51.49 mL at 30 weeks. Assessment of agreement was studied by selection of 40 volumes. Intraobserver variability was 5.48 mL (10.6%) and 3.07 mL (5.96%). Interobserver variability was 7 mL.

CONCLUSIONS: Our findings suggest that 3-dimensional ultrasonographically derived measurements are reliable and reproducible up to 30 weeks if a standard measurement technique is used.

Volume

23

Issue

3

First Page

347

Last Page

352

ISSN

0278-4297

Published In/Presented At

Sabogal, J. C., Becker, E., Bega, G., Komwilaisak, R., Berghella, V., Weiner, S., & Tolosa, J. (2004). Reproducibility of fetal lung volume measurements with 3-dimensional ultrasonography. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 23(3), 347–352. https://doi.org/10.7863/jum.2004.23.3.347

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

15055781

Department(s)

Administration and Leadership

Document Type

Article