Does midtrimester cervical length ≥25 mm predict preterm birth in high-risk women?
Publication/Presentation Date
10-1-2010
Abstract
OBJECTIVE: We sought to assess pregnancy outcome along a continuum of cervical lengths (CLs) ≥25 mm.
STUDY DESIGN: We conducted planned secondary analysis of a randomized cerclage trial of women with prior spontaneous preterm birth 17(0)-34(6/7) weeks. Outcomes of women who maintained CLs ≥25 mm were analyzed. Women with CLs < 25 mm randomized to no cerclage comprised an internal comparison group.
RESULTS: Of 1014 screened, 153 had CL < 25 mm, and 672 had CL ≥25 mm. Birth < 35 weeks occurred in 16% of the ≥25 mm cohort. The relationship between CLs ≥25 mm and birth gestational age was null (P = .15). In the < 25 mm group, progressively shorter CLs predicted birth < 35 weeks (P < .001); this relationship was null in the ≥25 mm group (P = .17).
CONCLUSION: The continuum of CLs ≥25 mm measured between 16(0/7)-22(6/7) weeks does not predict gestational length in women with prior spontaneous preterm birth.
Volume
203
Issue
4
First Page
1
Last Page
5
ISSN
1097-6868
Published In/Presented At
Owen, J., Szychowski, J. M., Hankins, G., Iams, J. D., Sheffield, J. S., Perez-Delboy, A., Berghella, V., Wing, D. A., Guzman, E. R., & Vaginal Ultrasound Trial Consortium (2010). Does midtrimester cervical length ≥25 mm predict preterm birth in high-risk women?. American journal of obstetrics and gynecology, 203(4), 393.e1–393.e3935. https://doi.org/10.1016/j.ajog.2010.06.025
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
20708169
Department(s)
Administration and Leadership
Document Type
Article