Gestational age of previous twin preterm birth as a predictor for subsequent singleton preterm birth.
Publication/Presentation Date
2-1-2012
Abstract
OBJECTIVE: We sought to determine an optimal gestational-age cutoff of preterm twin deliveries for predicting subsequent singleton preterm birth (PTB).
STUDY DESIGN: We performed a retrospective study of women with a spontaneous twin delivery who subsequently had a singleton gestation. Univariate and multivariate analyses determined the risk of a spontaneous singleton PTB after a PTB of a twin gestation. Different gestational-age cutoffs of the previous twin PTB were evaluated.
RESULTS: Among 255 women, previous twin PTB at < 34 weeks' gestation was associated with an increased risk of singleton PTB (odds ratio, 9.67; 95% confidence interval, 3.07-30.47). Every twin gestational age cutoff at < 34 weeks' gestation had a significantly higher risk of subsequent singleton PTB, which was no longer significant at ≥ 34 weeks' gestation (odds ratio, 1.68; 95% confidence interval, 0.23-12.19).
CONCLUSION: In women with a previous spontaneous twin PTB at < 34 weeks' gestation, there is an increased risk of subsequent singleton PTB. A twin birth at ≥ 34 weeks' gestation is not associated with an increased risk for a subsequent singleton PTB.
Volume
206
Issue
2
First Page
1
Last Page
6
ISSN
1097-6868
Published In/Presented At
Rafael, T. J., Hoffman, M. K., Leiby, B. E., & Berghella, V. (2012). Gestational age of previous twin preterm birth as a predictor for subsequent singleton preterm birth. American journal of obstetrics and gynecology, 206(2), 156.e1–156.e1566. https://doi.org/10.1016/j.ajog.2011.10.008
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
22098669
Department(s)
Administration and Leadership
Document Type
Article