Fatal aortic dissection in a patient with a family history of Marfan syndrome.
Publication/Presentation Date
8-1-2008
Abstract
BACKGROUND: Marfan syndrome has great genotypic and phenotypic variability. Marfan syndrome patients face an increased risk of maternal and fetal complications during and after pregnancy.
CASE: A 5-ft, 4-in-tall 40-year-old gravida 4 para 2 with a family history of Marfan syndrome presented 4 days after spontaneous vaginal delivery with sudden onset of shortness of breath, air hunger, syncope, and collapse, with resultant asystole. Resuscitation attempts were unsuccessful, and postmortem findings showed dissection and cystic medial necrosis of the aorta.
CONCLUSION: Regardless of physical appearance, any patient reporting a family history of Marfan syndrome should undergo and have documented a thorough multidisciplinary evaluation of the skeletal, ocular, cardiovascular, pulmonary, and skin/integumentary systems and dura, in addition to genetic counseling.
Volume
112
Issue
2 Pt 2
First Page
472
Last Page
475
ISSN
0029-7844
Published In/Presented At
Birsner, M. L., Farber, J. L., & Berghella, V. (2008). Fatal aortic dissection in a patient with a family history of Marfan syndrome. Obstetrics and gynecology, 112(2 Pt 2), 472–475. https://doi.org/10.1097/AOG.0b013e3181743312
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
18669769
Department(s)
Administration and Leadership
Document Type
Article