Myasthenia gravis, thymoma, and intestinal pseudo-obstruction: a case report and review.

Authors

• Goran Rakocevic
• Richard Barohn
• April L McVey
• Ivan Damjanov
• Paul D Morte
• Steven Vernino
• Vanda Lennon

Publication/Presentation Date

12-1-2003

Abstract

We report a 28-year-old man who presented with intestinal pseudo-obstruction as the initial manifestation of thymoma, myasthenia gravis, and dysautonomia. The patient's autoantibody profile was characteristic of this constellation of disorders, being positive for both muscle and ganglionic nicotinic acetylcholine receptor antibodies and striational antibody. Inflammatory cell infiltrates were found in the myenteric plexus of the stomach and small intestine. Review of 12 previously reported cases suggests that patients with both myasthenia gravis and dysautonomia in the context of thymoma respond poorly to therapy.

Volume

5

Issue

2

First Page

93

Last Page

95

ISSN

1537-1611

Published In/Presented At

Rakocevic, G., Barohn, R., McVey, A. L., Damjanov, I., Morte, P. D., Vernino, S., & Lennon, V. (2003). Myasthenia gravis, thymoma, and intestinal pseudo-obstruction: a case report and review. Journal of clinical neuromuscular disease, 5(2), 93–95. https://doi.org/10.1097/00131402-200312000-00004

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

19078726

Department(s)

Administration and Leadership

Document Type

Article