Integrated Lymphopenia Analysis in Younger and Older Patients With Multiple Sclerosis Treated With Cladribine Tablets.

Authors

• Gavin Giovannoni
• Patricia K Coyle
• Patrick Vermersch
• Bryan Walker
• Julie Aldridge
• Axel Nolting
• Andrew Galazka
• Caroline Lemieux
• Thomas P Leist

Publication/Presentation Date

1-1-2021

Abstract

Cladribine tablets (CladT) preferentially reduce B and T lymphocyte levels. As aging is associated with a decline in immune function, the effect of CladT on lymphocyte levels may differ by age. This

Volume

12

First Page

763433

Last Page

763433

ISSN

1664-3224

Published In/Presented At

Giovannoni, G., Coyle, P. K., Vermersch, P., Walker, B., Aldridge, J., Nolting, A., Galazka, A., Lemieux, C., & Leist, T. P. (2021). Integrated Lymphopenia Analysis in Younger and Older Patients With Multiple Sclerosis Treated With Cladribine Tablets. Frontiers in immunology, 12, 763433. https://doi.org/10.3389/fimmu.2021.763433

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

35003076

Department(s)

Administration and Leadership

Document Type

Article