Rosai-Dorfman disease with cutaneous plaques and autoimmune haemolytic anemia.

Authors

• Sweta Subhadarshani
• Tarun Kumar
• Sudheer Arava
• Somesh Gupta

Publication/Presentation Date

11-24-2019

Abstract

Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) is a non-Langerhan cell histiocytosis which primarily involves lymph nodes. Extranodal involvement in the form of cutaneous plaques can occur and can pose a diagnostic challenge because of pleomorphic presentation and histopathological mimics. Rarely, systemic autoimmune involvement may complicate the disease process. We present a 28-year-old woman with slowly evolving scaly erythematous cutaneous plaques and fluctuating lymphadenopathy, associated with autoimmune haemolytic anaemia. The patient responded favourably to oral corticosteroids and acitretin with significant flattening of cutaneous plaques, reduction in size of neck nodes and improvement of anaemia.

Volume

12

Issue

11

ISSN

1757-790X

Published In/Presented At

Subhadarshani, S., Kumar, T., Arava, S., & Gupta, S. (2019). Rosai-Dorfman disease with cutaneous plaques and autoimmune haemolytic anemia. BMJ case reports, 12(11), e231927. https://doi.org/10.1136/bcr-2019-231927

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

31767610

Department(s)

Administration and Leadership

Document Type

Article