Peri-operative fever and LVAD: SIRS or impaired right ventricular strain?
Publication/Presentation Date
10-1-2024
Abstract
BACKGROUND: An inflammatory milieu after left ventricular assist device (LVAD) implantation is associated with multi-organ dysfunction and pre-operative heightened inflammatory state is associated with right ventricular failure after LVAD implantation.
METHODS: We performed a retrospective analysis of 30 LVAD patients in our institution within the last 2 years for the development of fever and compared them to 30 non-LVAD open-heart surgery patients.
RESULTS: Our results suggest that patients undergoing LVAD implantation are more likely to develop fever in the immediate post-operative period compared to other open-heart surgeries. This is independent of pharmacological treatment, age, or ethnical background. Females and obese patients were more likely to develop fever.
CONCLUSION: Patients with right ventricular dysfunction, as demonstrated by elevated central venous pressure (CVP), had the strongest correlation with fever development. These results pose the question if there is a systemic inflammatory response-like phenomenon driven by increased right ventricular dysfunction.
Volume
48
Issue
10
First Page
1162
Last Page
1167
ISSN
1525-1594
Published In/Presented At
Marek-Iannucci, S., Wildemann, R., Brailovsky, Y., Dyer, S., Gamero, M. T., Alvarez, R. J., Rame, E., Massey, H. T., Tchantchaleishvili, V., Thoma, B., & Rajapreyar, I. N. (2024). Peri-operative fever and LVAD: SIRS or impaired right ventricular strain?. Artificial organs, 48(10), 1162–1167. https://doi.org/10.1111/aor.14803
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
38887186
Department(s)
Administration and Leadership
Document Type
Article