Unexpected normal ROTEM results in protein C deficiency with IVC thrombosis.
Publication/Presentation Date
11-17-2024
Abstract
Protein C deficiency is a hereditary disorder that increases the risk of thrombotic events but has unclear effects on rotational thromboelastometry (ROTEM) analysis. A man in his 60s with a history of protein C deficiency and multiple thrombotic events underwent inferior vena cava (IVC) filter removal, iliocaval thrombectomy and infrarenal IVC placement for IVC-related complete iliocaval and common femoral vein thromboses. A ROTEM analysis showed normal coagulation in NATEM and EXTEM and only a slight shortening in A10 and A20 in INTEM, which was unexpected given his diagnosis of protein C deficiency. Normal results indicate that there is complexity and variability of coagulation to maintain a balanced state even in individuals with underlying coagulation disorders.
Volume
17
Issue
11
ISSN
1757-790X
Published In/Presented At
Kim, R. S., & Yoon, U. (2024). Unexpected normal ROTEM results in protein C deficiency with IVC thrombosis. BMJ case reports, 17(11), e262718. https://doi.org/10.1136/bcr-2024-262718
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
39551573
Department(s)
Administration and Leadership
Document Type
Article