Well-Differentiated Lung Neuroendocrine Tumor Masquerading as Metastatic Medullary Thyroid Cancer.
Publication/Presentation Date
9-1-2025
Abstract
Typical carcinoid tumors, or low-grade neuroendocrine tumors (NETs), are a rare class of neoplasms that share histopathological characteristics with other NETs like medullary thyroid cancer (MTC). Here, we report an 85-year-old woman with a history of left hemithyroidectomy in the 1980s (pathology not available) and right-sided multinodular goiter biopsied as benign, initially misdiagnosed with metastatic MTC based on lung nodule biopsy staining for calcitonin. The lung nodule was surgically removed and shown to be a well-differentiated lung NET. This case demonstrates the diagnostic challenges of integrating cytopathological findings, such as calcitonin staining, with the overall clinical scenario to arrive at an accurate diagnosis.
Volume
3
Issue
9
First Page
172
Last Page
172
ISSN
2755-1520
Published In/Presented At
Stezzi, M., Brose, M., Gordon, S. W., Solomides, C., Tuluc, M., & Miller, J. (2025). Well-Differentiated Lung Neuroendocrine Tumor Masquerading as Metastatic Medullary Thyroid Cancer. JCEM case reports, 3(9), luaf172. https://doi.org/10.1210/jcemcr/luaf172
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
40746501
Department(s)
Administration and Leadership
Document Type
Article