Hormone Replacement Therapy Is Associated with Disease Activity Improvement among Post-Menopausal Women with Inflammatory Bowel Disease.

Authors

• Morgan Freeman
• Lauren Lally
• Levi Teigen
• Elliot Graziano
• Raina Shivashankar
• Eugenia Shmidt

Publication/Presentation Date

12-23-2023

Abstract

(1) Background: There are limited data available to guide clinical decision-making regarding the effects of hormone replacement therapy (HRT) in post-menopausal women with inflammatory bowel disease (IBD). In this study, we sought to characterize a population of post-menopausal women with IBD and to determine the effects of HRT on their disease activity. (2) Methods: A multicenter, retrospective, case-control cohort study of post-menopausal women with IBD was conducted. The physician global assessment (PGA) score was used to quantify disease activity. To control for the effects of menopause, IBD patients who had not undergone HRT were used as controls. (3) Results: There was a significant reduction in the frequency of PGA scores ≥2 post HRT treatment (

Volume

13

Issue

1

ISSN

2077-0383

Published In/Presented At

Freeman, M., Lally, L., Teigen, L., Graziano, E., Shivashankar, R., & Shmidt, E. (2023). Hormone Replacement Therapy Is Associated with Disease Activity Improvement among Post-Menopausal Women with Inflammatory Bowel Disease. Journal of clinical medicine, 13(1), 88. https://doi.org/10.3390/jcm13010088

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

38202098

Department(s)

Administration and Leadership

Document Type

Article