EUS-guided Gastroenterostomy: A Multicenter International Study Comparing Benign and Malignant Diseases.
Publication/Presentation Date
7-1-2024
Abstract
BACKGROUND: Endoscopic ultrasound (EUS)-guided gastroenterostomy (EUS-GE) is a minimally invasive therapy for patients with gastric outlet obstruction without the risks of surgical bypass and the limited long-term efficacy of enteral self-expanding metal stent placement. However, due to its novelty, there is a lack of significant data comparing long-term outcomes of patients with EUS-GE, based on the underlying disease. In this study, we compare outcomes of EUS-GE on benign versus malignant indications.
METHODS: Consecutive patients from 12 international, tertiary care centers who underwent EUS-GE over 3 years were extracted in a retrospective registry. Demographic characteristics, procedure-related information and follow-up data was collected. Primary outcome was the rate of adverse events associated with EUS-GE and the comparison of the rate of adverse events in benign versus malignant diseases. Secondary outcomes included technical and clinical success as well as hospitalization admission.
RESULTS: A total of 103 patients were included: 72 malignant and 31 benign. The characteristics of the patients undergoing EUS-GE is shown in Table 1. The mean age of the cohort was 68 years and 58 years for malignant and benign etiology. Gender distribution was 57% and 39% being females in malignant and benign etiology group, respectively. Clinical success, technical success, average procedure time, and hospital length of stay were similar in both groups. Patients with benign underlying etiology had significantly higher number of surgically altered midgut anatomy ( P =0.0379).
CONCLUSION: EUS-GE is equally efficient regardless of the underlying etiology (malignant vs. benign), and the adverse events both groups were comparable.
Volume
58
Issue
6
First Page
570
Last Page
573
ISSN
1539-2031
Published In/Presented At
Kahaleh, M., Tyberg, A., Sameera, S., Sarkar, A., Shahid, H. M., Abdelqader, A., Gjeorgjievski, M., Gaidhane, M., Muniraj, T., Jamidar, P. A., Aslanian, H. R., Abraham, M., Lajin, M., Kedia, P., Nieto, J., Parsa, N., Andalib, I., Bashir, M., Kowalski, T. E., Loren, D. E., … Barthet, M. (2024). EUS-guided Gastroenterostomy: A Multicenter International Study Comparing Benign and Malignant Diseases. Journal of clinical gastroenterology, 58(6), 570–573. https://doi.org/10.1097/MCG.0000000000001903
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
37646532
Department(s)
Administration and Leadership
Document Type
Article