The epidemiology, evaluation and treatment of stroke in adults with sickle cell disease.
Publication/Presentation Date
12-1-2011
Abstract
Stroke is a frequent and severe complication in adults with sickle cell disease. Ischemic stroke often causes physical and cognitive disability, while hemorrhagic stroke has a high mortality rate. As more children survive, the number of strokes in adults is increasing, yet stroke remains poorly understood. We review the epidemiology of ischemic and hemorrhagic stroke in adults with sickle cell disease and outline a practical approach to the evaluation of stroke including both sickle cell disease specific and general risk factors. We discuss the acute treatment and secondary prevention of stroke in this population based on the evidence in children with sickle cell disease and the general population, in addition to the limited studies in adults with sickle cell disease.
Volume
4
Issue
6
First Page
597
Last Page
606
ISSN
1747-4094
Published In/Presented At
Strouse, J. J., Lanzkron, S., & Urrutia, V. (2011). The epidemiology, evaluation and treatment of stroke in adults with sickle cell disease. Expert review of hematology, 4(6), 597–606. https://doi.org/10.1586/ehm.11.61
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
22077524
Department(s)
Administration and Leadership
Document Type
Article