Liver Transplant in Hemoglobin SC Disease and Autoimmune Hepatitis: A Case Report.
Publication/Presentation Date
4-1-2022
Abstract
Although liver transplant is a life-saving measure for individuals with end-stage liver disease, the perioperative management may be challenging in individuals with concomitant sickle cell disease. We report a case of a 50-year-old man with sickle cell disease genotype SC (HbSC) and cirrhosis secondary to autoimmune hepatitis who underwent liver transplant. His postoperative course included upper extremity deep vein thrombosis, pulmonary embolus, stroke via a patent foramen ovale after a line removal, and posterior reversible encephalopathy syndrome. Fortunately, he is alive with a functioning graft at 10 months after liver transplant. This case highlights the feasibility of liver transplant in sickle cell disease given the support of meticulous multidisciplinary care and the unique aspects of autoimmune hepatitis and sickle cell disease for liver transplant consideration.
Volume
20
Issue
4
First Page
429
Last Page
432
ISSN
2146-8427
Published In/Presented At
Kim, A., Assarzadegan, N., Anders, R. A., Oshima, K., Chaturvedi, S., Weeks, S., Kohli, R., Lanzkron, S., Gurakar, A., Garonzik-Wang, J., & Chen, P. H. (2022). Liver Transplant in Hemoglobin SC Disease and Autoimmune Hepatitis: A Case Report. Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, 20(4), 429–432. https://doi.org/10.6002/ect.2021.0350
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
34981707
Department(s)
Administration and Leadership
Document Type
Article