Diminished ovarian reserve in young women with sickle cell anemia.

Authors

• Lydia H Pecker
• Sarah Hussain
• Jaanvi Mahesh
• Ravi Varadhan
• Mindy S Christianson
• Sophie Lanzkron

Publication/Presentation Date

2-17-2022

Abstract

Women with sickle cell anemia (SCA) have higher rates of diminished ovarian reserve (DOR) than age-matched controls. Pecker et al report a small study of patients with SCA that compares ovarian reserve in patients after stem cell transplant, on therapy with hydroxyurea (HU), and on supportive care. As expected, patients who received transplants have severe DOR. About one-third of patients on HU have DOR, while DOR was absent in patients on supportive care. Whether this reflects an impact of HU or is a biomarker of severe disease remains to be established in a larger study.

Volume

139

Issue

7

First Page

1111

Last Page

1115

ISSN

1528-0020

Published In/Presented At

Pecker, L. H., Hussain, S., Mahesh, J., Varadhan, R., Christianson, M. S., & Lanzkron, S. (2022). Diminished ovarian reserve in young women with sickle cell anemia. Blood, 139(7), 1111–1115. https://doi.org/10.1182/blood.2021012756

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

34864892

Department(s)

Administration and Leadership

Document Type

Article