Short-term air pollution levels and sickle cell disease hospital encounters in South Carolina: A case-crossover analysis.
Publication/Presentation Date
7-1-2024
Abstract
BACKGROUND: Sickle cell disease (SCD) is a genetic disorder and symptoms may be sensitive to environmental stressors. Although it has been hypothesized that exposure to outdoor air pollution could trigger acute SCD events, evidence is limited.
METHODS: We obtained SCD administrative data on hospital encounters in South Carolina from 2002 to 2019. We estimated outdoor air pollutant (particulate matter< 2.5 μm (PM
RESULTS: We studied 8410 patients with 144,129 hospital encounters. We did not observe associations among all patients with SCD and adults for PM
CONCLUSIONS: Our findings suggest that short-term (within two-weeks) levels of EC and O
Volume
252
Issue
Pt 1
First Page
118766
Last Page
118766
ISSN
1096-0953
Published In/Presented At
Wen, T., Puett, R. C., Liao, D., Kanter, J., Mittleman, M. A., Lanzkron, S. M., & Yanosky, J. D. (2024). Short-term air pollution levels and sickle cell disease hospital encounters in South Carolina: A case-crossover analysis. Environmental research, 252(Pt 1), 118766. https://doi.org/10.1016/j.envres.2024.118766
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
38583660
Department(s)
Administration and Leadership
Document Type
Article