EIF1AX Mutation in a Patient with Hürthle Cell Carcinoma.

Authors

• Michael C Topf
• Zi-Xuan Wang
• Kevin Furlong
• Jeffrey L Miller
• Madalina Tuluc
• Edmund A Pribitkin

Publication/Presentation Date

3-1-2018

Abstract

The EIF1AX gene is a novel cancer gene that has been reported in the tumorigenesis of papillary thyroid carcinoma, follicular variant papillary thyroid carcinoma, and anaplastic thyroid carcinoma. A 71-year-old woman presented with a right thyroid mass, which was follicular neoplasm on cytology. The fine needle aspirate of the nodule was examined by next-generation sequencing and found to harbor EIF1AX and TP53 mutations. Right thyroid lobectomy was performed with final pathology showing Hürthle cell carcinoma with capsular and vascular invasion. We report an EIF1AX mutation in a patient found to have Hürthle cell carcinoma.

Volume

29

Issue

1

First Page

27

Last Page

29

ISSN

1559-0097

Published In/Presented At

Topf, M. C., Wang, Z. X., Furlong, K., Miller, J. L., Tuluc, M., & Pribitkin, E. A. (2018). EIF1AX Mutation in a Patient with Hürthle Cell Carcinoma. Endocrine pathology, 29(1), 27–29. https://doi.org/10.1007/s12022-017-9501-8

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

28965201

Department(s)

Administration and Leadership

Document Type

Article