Woven EndoBridge device for ruptured aneurysms: perioperative results of a US multicenter experience.
Publication/Presentation Date
11-1-2021
Abstract
BACKGROUND: The Woven EndoBridge (WEB) device is approved in the USA for treatment of unruptured wide-neck bifurcation aneurysms. However, the safety and effectiveness of the WEB device in the treatment of ruptured intracranial aneurysms is not clear. We aim to evaluate the perioperative safety and effectiveness of the WEB device in patients with ruptured intracranial aneurysms.
METHODS: This retrospective study, conducted at eight centers in the USA, included patients with ruptured intracranial aneurysms treated with the WEB device in the setting of subarachnoid hemorrhage (SAH). Safety outcomes included intraoperative complications such as vessel perforation, thromboembolic events, and postoperative hemorrhagic or thromboembolic complications based on radiologic imaging. The primary effectiveness outcome was adequate (complete and neck remnant) aneurysm occlusion, according to the Raymond-Roy classification.
RESULTS: A total of 91 patients with 94 ruptured intracranial aneurysms were included (mean age 57.7±15.2 years; 68.1% women; 82.9% wide-necked). Aneurysms were located in the anterior communicating artery (42/94, 44.6%), middle cerebral artery (16/94, 17%), and basilar artery (15/94, 16%). Adequate occlusion was achieved in 48.8% (41/84) and 80.0% (40/50) at discharge and last follow-up (mean of 3.4 months), respectively. At discharge, procedural-related morbidity was 3.3% (3/91) and there was no procedure-related mortality. No re-rupture or delayed aneurysm rupture was observed.
CONCLUSIONS: This study demonstrates the perioperative safety and effectiveness of the WEB device for the treatment of patients with ruptured intracranial aneurysms in the setting of SAH, with low periprocedural morbidity and mortality. Long-term follow-up is warranted.
Volume
13
Issue
11
First Page
1012
Last Page
1016
ISSN
1759-8486
Published In/Presented At
Cortez, G. M., Akture, E., Monteiro, A., Arthur, A. S., Peterson, J., Dornbos, D., Jabbour, P., Gooch, M. R., Sweid, A., Tjoumakaris, S. I., Delgado Almandoz, J. E., Kayan, Y., Rai, A. T., Boo, S., Fiorella, D., Vachhani, J., Foreman, P., Cress, M., Siddiqui, A. H., Waqas, M., … Hanel, R. A. (2021). Woven EndoBridge device for ruptured aneurysms: perioperative results of a US multicenter experience. Journal of neurointerventional surgery, 13(11), 1012–1016. https://doi.org/10.1136/neurintsurg-2020-017105
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
33483455
Department(s)
Administration and Leadership
Document Type
Article