A comparative analysis of microsurgical resection versus stereotactic radiosurgery for Spetzler-Martin grade III arteriovenous malformations: A multicenter propensity score matched study.
Publication/Presentation Date
2-1-2025
Abstract
BACKGROUND: Spetzler-Martin (SM) Grade III brain arteriovenous malformations (BAVMs) represent a transitional risk zone between low- and high-grade BAVMs, characterized by diverse angioarchitecture. The primary treatment options are endovascular embolization, microsurgical resection (MS), and stereotactic radiosurgery (SRS). This study compares the efficacy and outcomes of MS and SRS.
METHODS: We conducted a multicenter, retrospective study involving patients from the MISTA database with SM Grade III BAVMs treated with MS or SRS between 2010 and 2023. Propensity matching was based on age, favorable modified Rankin Score (mRS) at presentation, nidus size, rupture status, location depth, and eloquence.
RESULTS: After matching, 60 patients were equally divided between MS and SRS groups. Median age (MS: 45.0 vs. SRS: 42.5 years, p = 0.3) and AVM size (MS: 3.2 vs. SRS: 2.9 cm
CONCLUSION: MS and SRS are viable treatments for SM Grade III BAVMs. Treatment choice should be individualized by a multidisciplinary team, considering patient goals.
Volume
249
First Page
108669
Last Page
108669
ISSN
1872-6968
Published In/Presented At
Tos, S. M., Hajikarimloo, B., Osama, M., Mantziaris, G., Adeeb, N., Kandregula, S., Salim, H. A., Musmar, B., Ogilvy, C., Kondziolka, D., Dmytriw, A. A., El Naamani, K., Abdelsalam, A., Kumbhare, D., Gummadi, S., Ataoglu, C., Essibayi, M. A., Erginoglu, U., Keles, A., Muram, S., … Sheehan, J. (2025). A comparative analysis of microsurgical resection versus stereotactic radiosurgery for Spetzler-Martin grade III arteriovenous malformations: A multicenter propensity score matched study. Clinical neurology and neurosurgery, 249, 108669. https://doi.org/10.1016/j.clineuro.2024.108669
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
39642799
Department(s)
Administration and Leadership
Document Type
Article