Vertebrobasilar dolichoectasia future aspects: A meta-analysis of clinical features and treatment strategies.
Publication/Presentation Date
9-29-2025
Abstract
BackgroundDolichoectatic vertebrobasilar fusiform aneurysm (DVBFA) presents a clinical challenge due to its complex anatomical features and associated neurological complications. This meta-analysis evaluates the clinical outcomes of endovascular therapy (EVT), open surgery, and conservative management for DVBFA.MethodsA systematic review of the PubMed, Scopus, and Web of Science databases on July 18, 2024 was conducted to identify studies reporting on radiologically confirmed DVBFAs. Clinical outcomes were assessed using the modified Rankin Scale (mRS) and mortality rates. Meta-regression was performed to identify potential predictors of treatment outcomes.ResultsTen studies with 219 patients were analyzed. Of the cohort, 58.4% underwent EVT, 24.6% received open surgery, and 16.9% were managed conservatively. The overall proportion of patients achieving a good clinical outcome (mRS < 3) was 46.8%, with EVT showing the highest proportion at 59.4%, compared to 32.3% for open surgery and 24.7% for conservative management (
First Page
15910199251380385
Last Page
15910199251380385
ISSN
2385-2011
Published In/Presented At
Shaheen, N., Ortega-Gutierrez, S., Samaniego, E. A., Mastorakos, P., Gooch, M. R., Jabbour, P., Flouty, O., Dlouhy, K., & Zanaty, M. (2025). Vertebrobasilar dolichoectasia future aspects: A meta-analysis of clinical features and treatment strategies. Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 15910199251380385. Advance online publication. https://doi.org/10.1177/15910199251380385
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
41021786
Department(s)
Administration and Leadership
Document Type
Article