Predictors of Subjective Olfactory Dysfunction and Sinonasal Quality-of-Life After Endoscopic Transsphenoidal Pituitary Surgery.
Publication/Presentation Date
7-1-2024
Abstract
BACKGROUND: This is the largest study in North America investigating olfactory outcomes after pituitary surgery to date.
OBJECTIVE: Characterize factors associated with subjective olfactory dysfunction (OD) and worsened sinonasal quality-of-life (QOL) after endoscopic TSA.
METHODS: Patients undergoing primary TSA for secreting and non-secreting pituitary adenomas between 2017 and 2021 with pre- and post-operative SNOT-22 scores were included. Subjective OD was determined by the smell/taste dysfunction question on the SNOT-22 (smell-SNOT).
RESULTS: 159 patients with pre- and post-operative SNOT-22 scores were included. Average total SNOT-22 scores worsened from pre-operative (16.91 ± 16.91) to POM1 (25.15 ± 20.83,
CONCLUSION: Changes in subjective olfaction and sinonasal QOL after TSA may be associated with gender, operative approach, and intra-operative CSF leak, resolving 6-12 months post-operatively.
Volume
38
Issue
4
First Page
223
Last Page
229
ISSN
1945-8932
Published In/Presented At
Naimi, B. R., Farquhar, D., Duffy, A. N., Garvey, E. A., Kelly, P., Kahn, C., Doshi, R., Shah, R., Rabinowitz, M. R., Toskala, E., Rosen, M., Evans, J. J., & Nyquist, G. G. (2024). Predictors of Subjective Olfactory Dysfunction and Sinonasal Quality-of-Life After Endoscopic Transsphenoidal Pituitary Surgery. American journal of rhinology & allergy, 38(4), 223–229. https://doi.org/10.1177/19458924241243123
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
38646739
Department(s)
Administration and Leadership
Document Type
Article