Elevated T
Publication/Presentation Date
5-14-2026
Abstract
BACKGROUND AND PURPOSE: Acute ischemic stroke (AIS) due to M2 middle cerebral artery (MCA) occlusion represents the most frequent medium vessel occlusion (MeVO), yet the benefit of EVT in these patients remains uncertain. The perfusion parameter Tmax >4 seconds reflects delayed contrast arrival and captures regions of hemodynamic compromise that may include both potentially salvageable tissue and areas at risk of infarction if reperfusion is delayed or incomplete. This study therefore aims to evaluate whether the T
MATERIALS AND METHODS: For this retrospective multinational study, AIS patients with M2 MCA occlusion who underwent EVT were included. We performed univariable and multivariable logistic regression analysis to predict the mRS outcomes 90 days after the stroke (90-day mRS), based on the T
RESULTS: 130 M2 AIS patients were included, with a median age of 75.5 (65-81.75). The model based on T
CONCLUSIONS: Our results demonstrate that T
ISSN
1936-959X
Published In/Presented At
Kiani, I., Kooshki, A., Salim, H. A., Lakhani, D., Cho, A., Tsang, D., Adeeb, N., Li, Y. L., Zaccagna, F., Grist, J. T., Abuzahra, M. B., Essibayi, M. A., Colasurdo, M., Nguyen, T. N., Albers, G. W., Liebeskind, D. S., Heit, J. J., Faizy, T. D., Guenego, A., Dmytriw, A. A., … MAD MT Investigators (2026). Elevated Tmax >4 Seconds Volume Predicts Worse Functional Outcome Following Endovascular Treatment in M2 Middle Cerebral Artery Occlusion. AJNR. American journal of neuroradiology, ajnr.A9416. Advance online publication. https://doi.org/10.3174/ajnr.A9416
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
42134998
Department(s)
Administration and Leadership
Document Type
Article