Use of refractive index measurement for quality assurance of pediatric parenteral nutrient solutions.
Publication/Presentation Date
7-1-1987
Abstract
Use of refractive index measurements to assure accurate formulation of pediatric parenteral nutrient base solutions is described. The refractive indexes for various amino acid and dextrose concentrations were determined. An equation was derived to define the theoretical refractive index for combinations of amino acids and dextrose. Finally, a clinically acceptable range (deviation from theoretical) was determined. The actual refractive index for 300 pediatric parenteral nutrient solutions was compared with the calculated theoretical reading. The actual refractive index for all solutions was consistently predicted by the derived equation. Discussions with clinicians resulted in identification of an allowable range for these readings. All reading were within the identified range. The use of refractive index measurements is a valuable quality assurance tool for pediatric parenteral nutrient base formulations.
Volume
44
Issue
7
First Page
1617
Last Page
1620
ISSN
0002-9289
Published In/Presented At
Meyer, G. E., Novielli, K. A., & Smith, J. E. (1987). Use of refractive index measurement for quality assurance of pediatric parenteral nutrient solutions. American journal of hospital pharmacy, 44(7), 1617–1620.
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
3115096
Department(s)
Administration and Leadership
Document Type
Article