Immunity to Onchocerca spp. in animal hosts.
Publication/Presentation Date
4-1-2002
Abstract
This review summarizes research using Onchocerca spp. in chimpanzees, cattle and mice to gain insight into the protective immune response to the filarial worm Onchocerca volvulus in humans. In addition, Acanthocheilonema viteae has been evaluated as a surrogate filarial worm for studying immunity to the infection. Immune mechanisms controlling these infections are described and initial success using recombinant antigen vaccines in these models is reviewed.
Volume
18
Issue
4
First Page
164
Last Page
171
ISSN
1471-4922
Published In/Presented At
Abraham, D., Lucius, R., & Trees, A. J. (2002). Immunity to Onchocerca spp. in animal hosts. Trends in parasitology, 18(4), 164–171. https://doi.org/10.1016/s1471-4922(02)02245-6
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
11998704
Department(s)
Administration and Leadership
Document Type
Article