Renal dysfunction in heart failure patients: what is the evidence?
Publication/Presentation Date
3-1-2007
Abstract
Congestive heart failure (CHF) is an increasingly common medical condition and the fastest growing cardiovascular diagnosis in North America. Over one-third of patients with heart failure also have renal insufficiency. It has been shown that renal insufficiency confers worsened outcomes to patients with heart failure. However, a majority of the larger and therapy-defining heart failure medication and device trials exclude patients with advanced renal dysfunction. These studies also infrequently perform subgroup analyses based on the degree of renal dysfunction. The lack of information on heart failure patients who have renal insufficiency likely contributes to their being prescribed mortality and morbidity reducing medications and receiving diagnostic and therapeutic procedures at lower rates than heart failure patients with normal renal function. Inclusion of patients with renal insufficiency in heart failure studies and published guidelines for medication, device, and interventional therapies would likely improve patient outcomes.
Volume
12
Issue
1
First Page
37
Last Page
47
ISSN
1382-4147
Published In/Presented At
Saltzman, H. E., Sharma, K., Mather, P. J., Rubin, S., Adams, S., & Whellan, D. J. (2007). Renal dysfunction in heart failure patients: what is the evidence?. Heart failure reviews, 12(1), 37–47. https://doi.org/10.1007/s10741-007-9006-5
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
17393304
Department(s)
Administration and Leadership
Document Type
Article