Preservation of cranial nerve function after treatment of acoustic neurinomas with fractionated stereotactic radiotherapy. Preliminary observations in 26 patients.
Publication/Presentation Date
1-1-1995
Abstract
Twenty-seven acoustic tumors in 26 patients were treated with multiple fractionated linear-accelerator-based stereotactic radiotherapy (SRT). All patients with intact pretreatment facial nerve function with either small or large tumor volumes have thus far experienced no treatment-related facial neuropathy, including 9 patients with a mean follow-up of 22.4 +/- 1.6 months. The incidence of evaluable trigeminal neuropathy was 13%, and in 5 of 7 patients with serviceable pretreatment hearing, audiometry was unchanged in the immediate posttreatment period. Longer follow-up will be necessary to evaluate hearing preservation after SRT. Tumor response with central necrosis was seen in all assessable patients. SRT can be performed for cerebellopontine angle tumors with accuracy and reproducibility. It achieves a biological response similar to single fraction radiosurgery and may lower the incidence of facial and trigeminal neuropathies.
Volume
64
Issue
4
First Page
165
Last Page
182
ISSN
1011-6125
Published In/Presented At
Andrews, D. W., Silverman, C. L., Glass, J., Downes, B., Riley, R. J., Corn, B. W., Werner-Wasik, M., Curran, W. J., Jr, McCune, C. E., & Rosenwasser, R. H. (1995). Preservation of cranial nerve function after treatment of acoustic neurinomas with fractionated stereotactic radiotherapy. Preliminary observations in 26 patients. Stereotactic and functional neurosurgery, 64(4), 165–182. https://doi.org/10.1159/000098746
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
8817804
Department(s)
Administration and Leadership
Document Type
Article