Lung-Enriched Mutations in the p53 Tumor Suppressor: A Paradigm for Tissue-Specific Gain of Oncogenic Function.
Publication/Presentation Date
1-1-2019
Abstract
Lung cancer, the leading cause of cancer-related mortality in the United States, occurs primarily due to prolonged exposure to an array of carcinogenic compounds in cigarette smoke. These carcinogens create bulky DNA adducts, inducing alterations including missense mutations in the tumor suppressor gene
Volume
17
Issue
1
First Page
3
Last Page
9
ISSN
1557-3125
Published In/Presented At
Barta, J. A., & McMahon, S. B. (2019). Lung-Enriched Mutations in the p53 Tumor Suppressor: A Paradigm for Tissue-Specific Gain of Oncogenic Function. Molecular cancer research : MCR, 17(1), 3–9. https://doi.org/10.1158/1541-7786.MCR-18-0357
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
30224539
Department(s)
Administration and Leadership
Document Type
Article
COinS