Association of Smoking and Respiratory Disease History with Pancreatic Pathologies Requiring Surgical Resection.
Publication/Presentation Date
5-26-2023
Abstract
BACKGROUND: The purpose of this study was to examine the relationship between various respiratory conditions, including hypercapnic respiratory disease, and a multitude of resected pancreatic lesions.
METHODS: This retrospective case-control study queried a prospectively maintained database of patients who underwent pancreaticoduodenectomy between January 2015 and October 2021. Patient data, including smoking history, medical history, and pathology reports, were recorded. Patients with no smoking history and no concomitant respiratory conditions were designated as the control group.
RESULTS: A total of 723 patients with complete clinical and pathological data were identified. Male current smokers showed increased rates of PDAC (OR 2.33, 95% CI 1.07-5.08,
CONCLUSION: This large cohort study reveals possible links between respiratory pathologies and various pancreatic mass-forming lesions.
Volume
15
Issue
11
ISSN
2072-6694
Published In/Presented At
Ream, C., Sabitsky, M., Huang, R., Hammelef, E., Yeo, T. P., Lavu, H., Yeo, C. J., Bowne, W., & Nevler, A. (2023). Association of Smoking and Respiratory Disease History with Pancreatic Pathologies Requiring Surgical Resection. Cancers, 15(11), 2935. https://doi.org/10.3390/cancers15112935
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
37296897
Department(s)
Administration and Leadership
Document Type
Article