Colorectal cancer immunotherapy.

Authors

• Bo Xiang
• Adam E Snook
• Michael S Magee
• Scott A Waldman

Publication/Presentation Date

5-1-2013

Abstract

Antitumor immunotherapy for colorectal cancer has been studied at the bench and bedside for decades. Some clinical trials of cancer immunotherapy have demonstrated a potential benefit for patients with colorectal cancer, yet immunotherapy remains only an experimental option for this disease. Here, we review the major immunotherapeutic approaches currently under investigation for colorectal cancer, including cancer vaccines and adoptive cell therapy. Weakness and advantages of each strategy and progress in clinical trials will be described. Examination of previous and ongoing research in colorectal cancer therapy should define a path towards identification, approval, and mainstream adoption of colorectal cancer immunotherapeutics.

Volume

15

Issue

84

First Page

301

Last Page

308

ISSN

1944-7930

Published In/Presented At

Xiang, B., Snook, A. E., Magee, M. S., & Waldman, S. A. (2013). Colorectal cancer immunotherapy. Discovery medicine, 15(84), 301–308.

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

23725603

Department(s)

Administration and Leadership

Document Type

Article