Evaluating the Effect of Gastroesophageal Reflux Disease on Postoperative Dysphagia Following Anterior Cervical Spine Surgery-A Prospective, Multicenter Study.

Authors

• Aditya Mazmudar
• Taylor Paziuk
• John Mangan
• Khoa Tran
• Samuel Oh
• Sandy Li
• Brandon Sherrod
• Erica Bisson
• Darrel Brodke
• Christopher Kepler
• Gregory Schroeder
• Alexander Vaccaro
• Alan Hilibrand
• Jeffrey A Rihn

Publication/Presentation Date

6-1-2024

Abstract

STUDY DESIGN: Prospective cohort study.

OBJECTIVES: The purpose of this study was to prospectively evaluate the impact of a preoperative diagnosis of gastroesophageal reflux disease on the incidence and severity of postoperative dysphagia in a multicenter population.

METHODS: After Institutional Review Board approval, written informed consent was obtained from all participating patients. Patients over 18 years of age who underwent an elective anterior cervical discectomy and fusion for a degenerative condition were prospectively enrolled at two academic centers from the years 2018 to 2020. Patients were separated into two groups: those with and without a preoperative diagnosis of GERD. Continuous variables were assessed using either an independent t-test or Mann Whitney U-test for parametric and non-parametric data. All categorical variables were compared using a chi-square test.

RESULTS: A total of 116 patients met study criteria and were subsequently enrolled. Overall rates of postoperative dysphagia increased to 47.3% (n = 53) at 2-weeks but eventually decreased towards the preoperative prevalence of 25.0% at the 24-week mark. Patients with preoperative diagnosis of GERD had lower dysphagia severity scores on a continuous variable analysis in both the DSQ and EAT-10 surveys at 2-week follow-up in addition to the Bazaz survey at 24-week follow-up. Our follow up at 24-weeks was 85.7%.

CONCLUSIONS: Our study shows that having a preoperative diagnosis of GERD has no significant effect on the incidence of dysphagia following ACDF. Nevertheless, having a preoperative diagnosis of GERD does seem to provide some protective effect on the severity of dysphagia that this patient population develops at multiple intervals over a 24-week postoperative period.

Volume

14

Issue

5

First Page

1595

Last Page

1600

ISSN

2192-5682

Published In/Presented At

Mazmudar, A., Paziuk, T., Mangan, J., Tran, K., Oh, S., Li, S., Sherrod, B., Bisson, E., Brodke, D., Kepler, C., Schroeder, G., Vaccaro, A., Hilibrand, A., & Rihn, J. A. (2024). Evaluating the Effect of Gastroesophageal Reflux Disease on Postoperative Dysphagia Following Anterior Cervical Spine Surgery-A Prospective, Multicenter Study. Global spine journal, 14(5), 1595–1600. https://doi.org/10.1177/21925682231151645

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

36625340

Department(s)

Administration and Leadership

Document Type

Article