Cellular Bone Matrix Leading to Disseminated Tuberculosis After Spinal Fusion: A Report of 2 Cases.

Authors

• Tariq Z Issa
• Mark J Lambrechts
• Gregory R Toci
• Nicholas D D'Antonio
• Arun P Kanhere
• Kenneth Lingenfelter
• Gregory D Schroeder
• Alexander R Vaccaro

Publication/Presentation Date

4-1-2023

Abstract

CASE: Although implanted tuberculosis (TB) is rare, a single lot of cellular bone matrix was found to be infected with TB, leading to devastating outcomes. We present 2 cases referred to our institution because of instrumentation failure caused by TB inoculation of cellular bone matrix.

CONCLUSION: Irrespective of spinal region of implanted TB infection, excision of infected bone, extensive irrigation and debridement, and instrumented stabilization are of primary importance to ensure TB eradication and adequate stabilization.

Volume

13

Issue

2

ISSN

2160-3251

Published In/Presented At

Issa, T. Z., Lambrechts, M. J., Toci, G. R., D'Antonio, N. D., Kanhere, A. P., Lingenfelter, K., Schroeder, G. D., & Vaccaro, A. R. (2023). Cellular Bone Matrix Leading to Disseminated Tuberculosis After Spinal Fusion: A Report of 2 Cases. JBJS case connector, 13(2), 10.2106/JBJS.CC.23.00047. https://doi.org/10.2106/JBJS.CC.23.00047

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

37094038

Department(s)

Administration and Leadership

Document Type

Article