How are we defining preoperative anemia? A comparison of various anemia thresholds among patients undergoing short-construct lumbar spinal fusion.

Publication/Presentation Date

1-1-2025

Abstract

BACKGROUND: Anemia is a risk factor for increased transfusions. However, various definitions of anemia have been described in scientific literature and a consensus on how to appropriately diagnose anemia or who to preoperatively optimize is lacking. We aimed to compare multiple anemia definitions and evaluate if any threshold best predicts transfusion requirements and surgical outcomes following spinal fusion.

METHODS: We conducted a retrospective cohort study of 1-2 level posterior spinal fusions. Preoperative hemoglobin was defined based on preoperative laboratories within 28 days of surgery. Anemia was diagnosed using the World Health Organization (WHO), the American Society of Hematology (ASH), and the Cleveland Clinic (CC) thresholds. Youden's index and multivariable regressions were utilized to analyze associations of anemia with postoperative outcomes.

RESULTS: A total of 2257 patients were included. Patients who received a transfusion were more likely anemic regardless of definition (WHO: 60.0% vs. 14.0%,

CONCLUSIONS: Small variations in anemia definitions do not significantly impact the identification of patients necessitating a transfusion. However, the more discriminative WHO definition may best predict postoperative complications for lumbar fusions.

Volume

16

Issue

2

First Page

188

Last Page

194

ISSN

0974-8237

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

40756486

Department(s)

Administration and Leadership

Document Type

Article

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