Differential Impact of Depression and Psychotic Disorders on Complications, Costs, and Discharge After Single-Level Lumbar Fusion.

Authors

• Mitchell K Ng
• Leonidas E Mastrokostas
• Paul G Mastrokostas
• Gregorio Baek
• Jonathan Dalton
• Adam Fano
• Alec Giakas
• Rajendra Singh
• Afshin E Razi
• Arya Varthi
• Mark F Kurd
• Zachary Wilt
• Daniel R Fassett
• Alan S Hilibrand
• Alexander R Vaccaro
• Gregory D Schroeder
• Christopher K Kepler
• Andrew P Alvarez

Publication/Presentation Date

7-1-2026

Abstract

Study DesignRetrospective Cohort Study.ObjectivesMental health disorders like depression and psychoses are increasingly recognized in surgical populations and may adversely affect outcomes. This study aimed to: (1) evaluate the prevalence of these disorders among patients undergoing single-level lumbar fusion, (2) compare perioperative complications, costs, and discharge disposition; and (3) determine whether psychotic disorders confer greater risk than depression.MethodsA retrospective study of the National Inpatient Sample (2016-2022) identified adults undergoing elective single-level lumbar fusion procedures. Patients were stratified into depression, psychoses, or control cohorts. Multivariable logistic regression was adjusted for demographic, hospital, and clinical covariates and used to assess associations with perioperative complications, non-home discharge, and inpatient mortality. Hospital costs were converted and inflation-adjusted to 2022 United States (U.S.) dollars.ResultsAmong 792 065 weighted admissions, 17.7% had depression and 2.6% had psychotic disorders. Depression was independently associated with increased odds of cardiovascular complications (OR 1.26), mechanical complications (OR 1.25), adverse events (OR 1.26), and non-home discharge (OR 1.17, all

Volume

16

Issue

6

First Page

2718

Last Page

2726

ISSN

2192-5682

Published In/Presented At

Ng, M. K., Mastrokostas, L. E., Mastrokostas, P. G., Baek, G., Dalton, J., Fano, A., Giakas, A., Singh, R., Razi, A. E., Varthi, A., Kurd, M. F., Wilt, Z., Fassett, D. R., Hilibrand, A. S., Vaccaro, A. R., Schroeder, G. D., Kepler, C. K., & Alvarez, A. P. (2026). Differential Impact of Depression and Psychotic Disorders on Complications, Costs, and Discharge After Single-Level Lumbar Fusion. Global spine journal, 16(6), 2718–2726. https://doi.org/10.1177/21925682251414057

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

41452668

Department(s)

Administration and Leadership

Document Type

Article