Minimal Clinically Important Difference (MCID) and Long-Term Prospective Validation of the AO Spine PROST (Patient Reported Outcome Spine Trauma).
Publication/Presentation Date
4-18-2026
Abstract
Study designProspective observational multicenter cohort study.ObjectivesTo determine Minimal Clinically Important Difference (MCID) of AO Spine PROST (Patient Reported Outcome Spine Trauma) and conducting a long-term prospective validation.MethodsData were collected from a prospective observational international multicenter cohort study. Adults (18-65) with acute thoracolumbar (TL) burst fractures without neurologic deficits were enrolled, and followed for up to 2 years. Patients completed the AO Spine PROST, Oswestry Disability Index (ODI), EQ-5D, and Pain NRS. Characteristics were analyzed using descriptive statistics, MCID for PROST with distribution-based approach using the standard deviation (SD) of change in scores. Floor and ceiling effects were also evaluated. Internal consistency (Cronbach's alpha, item-total correlation coefficient (ITCC) and pairwise Spearman correlation), construct validity (Pearson correlations (r
First Page
21925682261445019
Last Page
21925682261445019
ISSN
2192-5682
Published In/Presented At
Sadiqi, S., Dandurand, C., Bransford, R. J., Benneker, L. M., Joaquim, A. F., Spiegl, U., Tee, J. W., Vaccaro, A. R., & Oner, F. C. (2026). Minimal Clinically Important Difference (MCID) and Long-Term Prospective Validation of the AO Spine PROST (Patient Reported Outcome Spine Trauma). Global spine journal, 21925682261445019. Advance online publication. https://doi.org/10.1177/21925682261445019
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
41999491
Department(s)
Administration and Leadership
Document Type
Article