Regional differences in cortical dendrite morphology following in utero exposure to cocaine.
Publication/Presentation Date
12-30-2003
Abstract
In utero exposure to cocaine has been shown to affect dopaminergic populations of developing neurons in the central nervous system (CNS). To determine if this was a regionally specific effect or the result of a global phenomenon, we used a Golgi-Cox analysis to measure several parameters of neuronal development in murine neurons from frontal cortex, a region of the cortex containing monoamine innervation, and somatosensory cortex, a monoamine sparse part of the cortex. Results of these analyses show that in utero exposure to cocaine affects total dendrite length in histotypical layers III and IV and dendritic volume in layer III of the frontal cortex. These effects are not present in the somatosensory cortex.
Volume
147
Issue
1-2
First Page
59
Last Page
66
ISSN
0165-3806
Published In/Presented At
Lloyd, S. A., Wensley, B., Faherty, C. J., & Smeyne, R. J. (2003). Regional differences in cortical dendrite morphology following in utero exposure to cocaine. Brain research. Developmental brain research, 147(1-2), 59–66. https://doi.org/10.1016/j.devbrainres.2003.09.008
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
14741751
Department(s)
Administration and Leadership
Document Type
Article