Radioimmunoassay for detection of anti-oligodendrocyte antibodies.

Authors

• A Rostami
• D E Pleasure
• R P Lisak
• D H Silberberg
• O Abramsky
• S M Phillips

Publication/Presentation Date

5-6-1981

Abstract

A solid phase radioimmunoassay (RIA) for detection and quantitation of rabbit anti-oligodendrocyte antibody has been developed using bovine oligodendroglia preparation. The assay is simple, rapid, reproducible and economical. It is approximately 150 x as sensitive as immunofluorescence. Specificity has been established by using different bovine tissue antigens as substrate and absorption studies. This assay represents a potentially powerful tool for the detection and quantitation of anti-oligodendroglial antibodies and oligodendroglial antigens in serum and CSF of man and experimental animals.

Volume

23

Issue

2

First Page

143

Last Page

148

ISSN

0304-3940

Published In/Presented At

Rostami, A., Pleasure, D. E., Lisak, R. P., Silberberg, D. H., Abramsky, O., & Phillips, S. M. (1981). Radioimmunoassay for detection of anti-oligodendrocyte antibodies. Neuroscience letters, 23(2), 143–148. https://doi.org/10.1016/0304-3940(81)90031-8

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

7254699

Department(s)

Administration and Leadership

Document Type

Article