Absence of neuroanatomical and behavioral deficits in L7/pcp-2-null mice.
Publication/Presentation Date
6-1-1997
Abstract
L7/pcp-2 is expressed exclusively in cerebellar Purkinje and retinal bipolar neurons. While the function of L7/pcp-2 is unknown, its mRNA is trafficked into dendrites, suggesting a role in dendritic physiology. To elucidate its function, L7/pcp-2-null mice were generated. These mice are neurologically normal with no signs of cerebellar or retinal dysfunction. The mice are indistinguishable from wild-type littermates with regards to gross neuroanatomy and fine structure of Purkinje cell dendrites.
Volume
46
Issue
1-2
First Page
333
Last Page
337
ISSN
0169-328X
Published In/Presented At
Vassileva, G., Smeyne, R. J., & Morgan, J. I. (1997). Absence of neuroanatomical and behavioral deficits in L7/pcp-2-null mice. Brain research. Molecular brain research, 46(1-2), 333–337. https://doi.org/10.1016/s0169-328x(97)00081-8
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
9191112
Department(s)
Administration and Leadership
Document Type
Article