3G11 expression in CD4+ T cell-mediated autoimmunity and immune tolerance.
Publication/Presentation Date
5-1-2011
Abstract
3G11 is a sialylated carbohydrate epitope of the disialoganglioside molecule expressed on mouse CD4(+) T cells. Recent research showed that 3G11 expression is related to the modulation of T cell function, i.e., 3G11(-) T cells exhibit anergic/Treg characteristics and efficiently inhibit autoimmunity in the central nervous system. The relationship between 3G11 expression and immune tolerance is summarized in this literature review.
Volume
11
Issue
5
First Page
593
Last Page
596
ISSN
1878-1705
Published In/Presented At
Zhou, F., Zhang, G. X., & Rostami, A. (2011). 3G11 expression in CD4+ T cell-mediated autoimmunity and immune tolerance. International immunopharmacology, 11(5), 593–596. https://doi.org/10.1016/j.intimp.2010.11.005
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
21084064
Department(s)
Administration and Leadership
Document Type
Article