New approaches to the prevention and eradication of rabies.
Publication/Presentation Date
6-1-2003
Abstract
Despite significant progress in improving the pre- and postexposure prophylaxis of human rabies, the development of better and more cost-effective vaccines and antiviral therapeutics remains a major goal for the treatment of human rabies, the control of animal rabies and particularly for the eradication of rabies virus reservoirs in terrestrial wildlife. In this review, we discuss the structural requirements for an effective rabies vaccine, as well as new strategies currently in use for the development of safer and more potent rabies vaccines for rabies prophylaxis and eradication. Finally, we discuss new immune therapeutics aimed at replacing the conventional administration of antirabies immunoglobulin used in rabies post-exposure prophylaxis in humans.
Volume
2
Issue
3
First Page
399
Last Page
406
ISSN
1476-0584
Published In/Presented At
Dietzschold, B., Faber, M., & Schnell, M. J. (2003). New approaches to the prevention and eradication of rabies. Expert review of vaccines, 2(3), 399–406. https://doi.org/10.1586/14760584.2.3.399
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
12903805
Department(s)
Administration and Leadership
Document Type
Article