The role of micronutrients in the diet of HIV-1-infected individuals.

Authors

• Giuseppe Nunnari
• Christian Coco
• Marilia Rita Pinzone
• Piero Pavone
• Massimiliano Berretta
• Michelino Di Rosa
• Matthias Schnell
• Giorgio Calabrese
• Bruno Cacopardo

Publication/Presentation Date

6-1-2012

Abstract

Vitamins, zinc and selenium are important micronutrients that play crucial functions at the cellular and molecular level. Immune response of several different cell types can be modulated by these micronutrients. Deficiency in micronutrients has been extensively reported in HIV-1-infected individuals and further correlated with CD4+ T-cell count, HIV-1 plasma viral load, disease progression and mortality. Supplementation by micronutrients has had controversial effects. Thorough future investigations and trials are certainly needed to strategically plan evidence-based interventions. Here, we review the available data on use of micronutrients during the course of HIV-1 infection.

Volume

4

Issue

7

First Page

2442

Last Page

2456

ISSN

1945-0508

Published In/Presented At

Nunnari, G., Coco, C., Pinzone, M. R., Pavone, P., Berretta, M., Di Rosa, M., Schnell, M., Calabrese, G., & Cacopardo, B. (2012). The role of micronutrients in the diet of HIV-1-infected individuals. Frontiers in bioscience (Elite edition), 4(7), 2442–2456. https://doi.org/10.2741/e556

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

22652651

Department(s)

Administration and Leadership

Document Type

Article