Current vaccine strategies against SARS-CoV-2: Promises and challenges.
Publication/Presentation Date
7-1-2022
Abstract
In the years since the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic began and spread across the globe, lessons have been learned about the challenges and opportunities that a pandemic brings to humankind. Researchers have produced many vaccines at unprecedented speed to protect people, but they have also been cognizant of the challenges presented by a new and unexpected infectious disease. The scope of this review is to examine the path of vaccine discovery so far and identify potential targets. Here, we provide insight into the leading vaccines and their advantages and challenges. We discuss the emerging mutations within the SARS-CoV-2 spike protein and other issues that need to be addressed to overcome coronavirus disease 2019 (COVID-19) completely. Future research is needed to develop a cheap, temperature-stable vaccine providing long-term immunity that protects the upper respiratory tract.
Volume
150
Issue
1
First Page
17
Last Page
21
ISSN
1097-6825
Published In/Presented At
Kurup, D., Myers, J., & Schnell, M. J. (2022). Current vaccine strategies against SARS-CoV-2: Promises and challenges. The Journal of allergy and clinical immunology, 150(1), 17–21. https://doi.org/10.1016/j.jaci.2022.05.008
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
35618046
Department(s)
Administration and Leadership
Document Type
Article