Imaging cortical association tracts in the human brain using diffusion-tensor-based axonal tracking.
Publication/Presentation Date
2-1-2002
Abstract
Diffusion-tensor fiber tracking was used to identify the cores of several long-association fibers, including the anterior (ATR) and posterior (PTR) thalamic radiations, and the uncinate (UNC), superior longitudinal (SLF), inferior longitudinal (ILF), and inferior fronto-occipital (IFO) fasciculi. Tracking results were compared to existing anatomical knowledge, and showed good qualitative agreement. Guidelines were developed to reproducibly track these fibers in vivo. The interindividual variability of these reconstructions was assessed in a common spatial reference frame (Talairach space) using probabilistic mapping. As a first illustration of this technical capability, a reduction in brain connectivity in a patient with a childhood neurodegenerative disease (X-linked adrenoleukodystrophy) was demonstrated.
Volume
47
Issue
2
First Page
215
Last Page
223
ISSN
0740-3194
Published In/Presented At
Mori, S., Kaufmann, W. E., Davatzikos, C., Stieltjes, B., Amodei, L., Fredericksen, K., Pearlson, G. D., Melhem, E. R., Solaiyappan, M., Raymond, G. V., Moser, H. W., & van Zijl, P. C. (2002). Imaging cortical association tracts in the human brain using diffusion-tensor-based axonal tracking. Magnetic resonance in medicine, 47(2), 215–223. https://doi.org/10.1002/mrm.10074
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
11810663
Department(s)
Administration and Leadership
Document Type
Article