Proton magnetic resonance spectroscopy of choroid plexus tumors in children.
Publication/Presentation Date
7-1-2001
Abstract
A variety of lesions may present as intraventricular masses in children. We report quantitative proton magnetic resonance spectroscopy (MRS) of two intraventricular tumors of the choroid plexus: choroid plexus carcinoma (CPC) and choroid plexus papilloma (CPP). Both lesions were characterized by high levels of choline-containing compounds and a complete absence of creatine and the neuronal/axonal marker N-acetyl aspartate. The CPC showed higher levels of choline compared to the CPP, and it also had elevated lactate. These preliminary results, if confirmed in a larger cohort of patients, indicate that proton MRS may have a role in the presurgical diagnosis of choroid plexus tumors in children, which may also have important implications for therapy and prognosis.
Volume
14
Issue
1
First Page
78
Last Page
82
ISSN
1053-1807
Published In/Presented At
Horská, A., Ulug, A. M., Melhem, E. R., Filippi, C. G., Burger, P. C., Edgar, M. A., Souweidane, M. M., Carson, B. S., & Barker, P. B. (2001). Proton magnetic resonance spectroscopy of choroid plexus tumors in children. Journal of magnetic resonance imaging : JMRI, 14(1), 78–82. https://doi.org/10.1002/jmri.1154
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
11436218
Department(s)
Administration and Leadership
Document Type
Article